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NUGoKidney & NU Nephrology will be at ASN Kidney Week

ASN Kidney Week 2019 is finally here! We've compiled a list of the 7 sessions, 9 oral poster presentations, and 45 posters featuring research from NUGoKidney and Northwestern Nephrology.

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Wednesday, November 6th 

Translational Session: Acid-Base, Fluid, and Electrolyte Balance Disorders: Challenging Issues for Clinicians

8:00 AM - 8:45 AM 
Normal-Gap Acidosis of Extrarenal Origin: Principles and Case Discussions
Speaker: Daniel Batlle, MD

11:30 AM - 12:00 PM 
Urine Studies for Acid-Base Balance
Speaker: Daniel Batlle, MD

Click here for full details on the session. 


Translational Session: Kidney Transplantation - VII. Challenges in Transplantation

3:45 PM - 4:15 PM
Monitoring of the Allograft, Subclinical Rejections, Protocol Biopsies, Donor-Specific Antibodies, and Novel Biomarkers
Speaker: John J. Friedewald, MD, FASN

5:15 PM - 6:00 PM 
Real-life Cases and Questions and Answers 
Speakers: John J. Friedewald, MD, FASN, Rita Alloway, PharmD, Roy D. Bloom, MD

Click here for full details on the session.

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Thursday, November 7th 

Translational Session: Needle Phobia: Kidney Transplant Biopsy Alternatives
12:00 PM - 12:30 PM 
Molecular Biomarkers in the Peripheral Blood
Speaker: John J. Friedewald, MD, FASN
Click here for full session details.
Basic/Clinical Science Session: Fibroblast Growth Factor 23 and Outcomes: New Answers, New Questions, Including the Jack W. Coburn, MD, Endowed Lectureship
2:00 PM - 4:00 PM 
Moderator(s): Tamara Isakova, MD; Carsten A. Wagner, MD
Click here for full session details. 
Special Session: Professional Development Session: Identifying and Navigating Your Career Path
6:00 PM - 6:30 PM 
Career Challenges Panel: Work-Life Integration and Time Management
Speaker(s): Cybele Ghossein, MDJohn K. Roberts, MD, MS; Lisa Robinson, MD, FASN; Craig Alan Shadur, MD, FASN
Click here for full session details. 
 
Posters - 10:00 AM - 12:00 PM

NUGoKidney Research Cores: Paving the Way for Breakthroughs in Kidney Therapeutics (INFO08-TH)
Full details and abstract here.


A Novel Angiotensin-Converting Enzyme 2 Truncate Markedly Improves Ischemic AKI (TH-PO008)
Full details and abstract here.
Inhibition of the VE-PTP Phosphatase Protects the Kidney from Ischemia-Reperfusion Injury (TH-PO046)
Full details and abstract here.
Differences in Disease Activity by Sex and Pubertal/Menopausal Status in Primary Glomerulonephropathies (TH-PO1046)
Full details and abstract here.
Discovery of CKD Patient Subgroups by Consensus Clustering: The CRIC Study (TH-PO385)
Full details and abstract here.
Plasma Biomarkers and the Association with Kidney Outcomes in African Americans with High-Risk Apolipoprotein L1 Variants (TH-PO411)
Full details and abstract here.
Associations of Plasma YKL-40 with Kidney Disease Progression, Mortality, and Histopathologic Lesions in Native Kidney Biopsies (TH-PO430)
Full details and abstract here.
Deoxycholic Acid and Mortality, ESRD, and Cardiovascular Events in Patients with CKD (TH-PO437)
Full details and abstract here.
Proximal Tubular Secretory Clearance Is Associated with the Progression of CKD: The CRIC Study (TH-PO457)
Full details and abstract here.
Dicer Promotes Renal Recovery and Limits Interstitial Fibrosis Following Kidney Injury (TH-PO505)
Full details and abstract here.
FGF23 Does Not Induce Left Ventricular Hypertrophy in Female Mice with CKD (TH-PO514)
Full details and abstract here.
Expression of an Anti-Fibrotic Molecule, Smad Anchor for Receptor Activation (SARA), Is Significantly Decreased in Kidneys of Patients with CKD (TH-PO567)
Full details and abstract here. 
Apparent Treatment-Resistant Hypertension (ATRH) Stratified by Ambulatory Blood Pressure Monitoring (ABPM) in CKD: A Report from the Chronic Renal Insufficiency Cohort (CRIC) Study (TH-PO686)
Full details and abstract here.
Abnormal Left Ventricular Metrics and Subsequent Cardiovascular Events in Japanese and US Patients with CKD: Findings from the CRIC and CKD-JAC Studies (TH-PO690) 
Full details and abstract here.
The Relationship of Change in Ankle Brachial Index with Mortality Among Individuals with CKD: The CRIC Study (TH-PO699)
Full details and abstract here. 
Natural History of Peripheral Artery Disease in Patients with CKD (TH-PO700)
Full details and abstract here. 
Distribution of Myocardial Fibrosis by Native T1 Times Using Cardiac Magnetic Resonance Measurements in CKD (TH-PO704)
Full details and abstract here.
A Young Adult Nephrology Transition Clinic: A Successful Model (TH-PO771)
Full details and abstract here.

Epithelial Membrane Protein 2 (EMP2) Is Predominantly Expressed in Vascular Smooth Muscle Cells of the Kidney (TH-PO805)
Full details and abstract here.

 
Oral Presentations

4:30 PM - 4:42 PM
Cell-Based Therapy and Podocyte Cell Fusion Rescue Type IV Collagen Composition in Alport Syndrome (TH-OR078)
Presenter: Valerie Lebleu, PhD
Full details and abstract here.


5:18 PM - 5:30 PM 
Lipocalin 2 Regulates FGF23 Production in CKD (TH-OR045)
Presenter: Guillaume Courbon, PhD, MSc
Full details and abstract here.


5:54 PM - 6:06 PM
Genetic Deletion of MIOX Ameliorates Obesity-Associated Tubulointerstitial Injury via Modulating O-GlcNAcylation of Sterol Regulatory Element Binding Protein (SREBP) (TH-OR065)
Presenter: Isha Sharma, PhD
Full details and abstract here.


6:18 PM - 6:30 PM
Functional Intrarenal Alterations and Morphological Glomerular Basement Changes in Mice Deficient of the Angiotensinase Aminopeptidase A (TH-OR087)
Presenter: Benedikt Marahrens
Full details and abstract here.

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Friday, November 8th 

Posters - 10:00 AM - 12:00 PM
Deletion of Proximal Tubular Cell VEGF Production Promotes Renal Fibrosis: Implications for VEGF-Based Cancer Therapy (FR-PO1003)
Full details and abstract here.
AKI in Renal Transplant Recipients Undergoing Cardiac Surgery (FR-PO1129)
Full details and abstract here.
Health-Related Quality of Life Among Kidney Transplant Patients Using the PROMIS Global Health Scale (FR-PO1150)
Full details and abstract here.
Kidney Recipients with Allograft Failure, Transition of Care (KRAFT): Practice Survey (FR-PO1168)
Full details and abstract here. 
Determinants of C-Terminal vs. Intact FGF-23 in CKD: The COMBINE Trial (FR-PO161)
Full details and abstract here. 
Deoxycholic Acid (DCA) and Coronary Artery Calcification (CAC) in the Chronic Renal Insufficiency Cohort (CRIC) (FR-PO285)
Full details and abstract here.
Expression of an Anti-Fibrotic Molecule Smad Anchor for Receptor Activation (SARA) Is Differentially Regulated in Epithelial Cells and Fibroblasts at a Translational Level (FR-PO348)
Full details and abstract here.
Integrative Omics Reveal Molecular Signatures of Endoplasmic Reticulum Stress in Tubular Epithelial Cells (FR-PO384)
Full details and abstract here.
Low Proteinuria Is Associated with Increased Mortality in Incident Dialysis Patients: Results from the CRIC Study (FR-PO431)
Full details and abstract here.
A Case of Scleroderma Renal Crisis in a Patient with Systemic Sclerosis Sine Scleroderma (FR-PO538)
Full details and abstract here.
Phenotype of Ksp-Cadherin Deficient Mice: Normal Kidney Development but Delayed Maturation of Maximal Urinary Concentrating Ability (FR-PO612)
Full details and abstract here.
A Comparison of the Effect of Sodium Bicarbonate on Acid-Base Indices in CKD Patients with and Without Diabetes: A Secondary Analysis of the BASE Pilot Trial (FR-PO634)
Full details and abstract here.
A Simple Equation to Estimate Urinary Flow Rate Using Urine Creatinine (FR-PO645)
Full details and abstract here.
A Case of IgG4-RD Manifesting as Kidney Disease: Idiopathic or Lymphoproliferative Etiology? (FR-PO668)
Full details and abstract here.
Hypophosphatemia from a Liver Spindle Cell Tumor: A Novel Site for FGF23-Related Tumor-Induced Osteomalacia (FR-PO677)
Full details and abstract here.
Endothelial-Specific Phosphatase VEPTP/PTPRB Is Essential for the Development of the Renal Mesangium (FR-PO760)
Full details and abstract here.

Defining the Role of Vascular Endothelial Growth Factor 3 (VEGFR3) in the Fenestrated Microvasculature Beds of the Kidney (FR-PO761)
Full details and abstract here.

 
Oral Poster Presentations

5:18 PM - 5:30 PM 
Molecular Regulation of Polycystin TRP Channels
Presenter: Paul DeCaen, PhD
Full details and abstract here.

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Saturday, November 9th 

Poster Presentations 10:00 AM - 12:00 PM
Phenotype of Ksp-Cadherin Deficient Mice: Enhanced Recovery from AKI (SA-PO070)
Full details and abstract here.

Overexpression of MIOX Accentuates Gentamycin-Induced Acute Tubular Injury via ALOX12-12HETE-GPR31 Signaling (SA-PO092)
Full details and abstract here.


Transgenic LPA Expression Does Not Exacerbate Albuminuria in Diabetic Mice (SA-PO532)
Full details and abstract here.

The Feasibility and Safety of Obtaining Research Kidney Biopsy Cores in Patients with Diabetes: An Interim Analysis of the TRIDENT Study (SA-PO541)
Full details and abstract here.


Association of Tubular Solute Clearances with the Glomerular Filtration Rate and Complications of CKD: The CRIC Study (SA-PO757)
Full details and abstract here.
Novel Truncated ACE2 Fusion Protein with Extended Half-Life Is Delivered to the Kidney and Ameliorates Angiotensin II-Induced Hypertension (SA-PO772)
Full details and abstract here.
Dietary Oxalate Ingestion, Urinary Oxalate Levels, and Response to Reloxaliase in Three Phase 2 Studies (SA-PO815)
Full details and abstract here.
Association of Educational Attainment with Incidence of CKD: Coronary Artery Risk Development in Young Adults (CARDIA) Study (SA-PO849)
Full details and abstract here.

Nitrite, Isoquercetin, and Endothelial Dysfunction Trial (NICE trial): Design and Preliminary Data (SA-PO912)
Full details and abstract here.

 
Oral Presentations
4:30 PM - 4:42 PM 
The Association of sTNFR-1 and sTNFR-2 with Histopathologic Lesions and Progression to ESRD: The Boston Kidney Biopsy Cohort Study
Presenter: Anand Srivastava, MD, MPH
Full details and abstract here.
4:42 PM - 4:54 PM
Two-Year Change in Galectin 3 and MMP-2 and Risk of ESRD: The Chronic Renal Insufficiency Cohort (CRIC) Study
Full details and abstract here.
5:06 PM - 5:18 PM 
C-FGF23 Peptide Protects Against Severe Hypoferremia During Acute Inflammation
Presenter(s): Guillaume Courbon; Vikas Chonira; Maralee Capella; Xueyan Wang; Aline Martin, PhD, MSc; Valentin David, PhD
Full details and abstract here.

5:42 PM - 5:54 PM
Carbamylation and the Risk of CKD Progression in the Chronic Renal Insufficiency Cohort (CRIC)
Full details and abstract here.

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Publications 

A Novel Genetic Model of Cystic Kidney Disease in the Mouse (PUB208)
Authors: Joshua Waitzman, MD, PhD; Ummiye Venus Onay, PhD; Susan Quaggin, MD
Read the abstract here.
Severe Microangiopathic Anemia in an ESRD Patient Unmasks Complement-Mediated Atypical Hemolytic-Uremic Syndrome (aHUS) and Successful Management with Treatment of aHUS (PUB543)
Authors: Shweta Punj, MD; Anthony Chang, MD; Vikram Aggarwal, MD 
Read the abstract here.
ANCA-Associated Glomerulonephritis with Linear GBM Staining in the Absence of Anti-GBM Antibody: A Variant of Double-Positive MPO and Anti-GBM Antibody (PUB575)
Authors: Janis Cho, MD; Yashpal Kanwar, MD, PhDVikram Aggarwal, MD 
Read the abstract here.

 

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