News and Announcements
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Director of NUGoKidney and American Society of Nephrology (ASN) President, Susan Quaggin, speaks to Northwestern Now about the commitment to eliminating health disparities that harm kidney patients. In July 2020, the NKF and ASN formed the NKF-ASN Task Force on Reassessing the Inclusion of Race in Diagnosing Kidney Diseases, releasing its final report online in the American Journal of Kidney Diseases (AJKD) and the Journal of the American Society of Nephrology (JASN).
Chicago KUH FORWARD's new NIDDK-funded TL1 interdisciplinary training program is now accepting applications for predoctoral and postdoctoral fellows in basic, translational, or clinical research in the fields of kidney, benign urologic, and benign hematologic diseases at one of the six Chicago KUH FORWARD partnering institutions: Ann & Robert H. Lurie Children's Hospital of Chicago, Loyola University, Northwestern University, Rush University, the University of Illinois at Chicago, and University of Chicago.
Apply for the Chicago KUH Fellowship today!
Join us for NUGoKidney webinar October 14th with special guest, Eun Ji Chung, PhD from the University of Southern California to explore the promise of nanomedicine for kidney disease and its potential as next-generation platforms for personalized medicine.
Dr. Chung will discuss the unique advantages of small organic micelles in target delivery of therapeutics for kidney disease including autosomal dominant polycystic kidney disease.
Register for the webinar today!
- Dinee Simpson, MD Works on Advancing Health Equity with Northwestern’s African American Transplant Access Program09.22.2021
Dinee Simpson, MD, assistant professor of Surgery in the Division of Organ Transplantation, discusses founding Northwestern Medicine’s African American Transplant Access Program (AATAP) in a recent Northwestern Medicine Magazine feature. Launching the program in 2019, Dr. Simpson speaks on the importance of kidney health equity and equal access to the best treatment for all patients.
Read the NM Magazine feature to learn more about how Dr. Simpson and AATAP has increased Black patients on transplant waiting list by 18% and the current project partnering with NUGoKidney and Endeleo Institute to create a culture of health and more.
- FUNDING OPPORTUNITY : Polycystic Kidney Disease Research Resource Consortium Pilot & Feasibility Program (Deadline: Sep 20th)08.27.2021
The Polycystic Kidney Disease Research Resource Consortium (PKD RRC) Pilot and Feasibility (P&F) Program is currently accepting applications aimed at the development of innovative and high-impact projects broadly related to the study of polycystic kidney and liver disease. Proposals focusing on discovery (hypothesis-generating) and/or innovative (high-risk/high-reward) research are highly encouraged. The program will support basic, translational and clinical research proposals.
Deadline to submit Letter of Intent: 4 pm CST on September 20, 2021
Deadline to submit applications: 4 pm CST on November 19, 2021
Additional information and eligibility can be found on the PKC RRC website here.
In an impressive and heartening poster showcase held on August 13th, we celebrated 13 remarkable budding young scientists and the conclusion of NUGoKidney’s 2021 SciHigh Summer Program, which provides students with mentorship, training, and hands-on experiences to build their skills and confidence in science and medicine.
This year’s hybrid program combined mentorship with in-person, hands-on experiences, and virtual interactive sessions led by experts in nephrology and other fields such as pediatrics, genetics, nanoscience, implementation science, and artificial intelligence to name a few.
Check out a recap of our summer of science here.
We are happy to announce the grants awarded from our recent call for proposals for our FY2022 NUGoKidney Pilot & Feasibility (P&F) Program. Of the many innovative, high-quality proposals we received, we were able to fund three new projects and renew one project for a second year, totaling nearly $150,000 in funds.
The kidney has largely been overlooked as a target organ for nanoparticle‑mediated drug delivery. On July 14, 2021, participants explored nephrotherapeutics development using nanotechnologies with Evan Scott, PhD, NUGoKidney Therapeutic Design and Development Core co-director. Dr. Scott discussed his ongoing work developing rationally designed nanomaterials for controlled targeted therapeutic delivery and potential applications to kidney therapeutics. Pinelopi Kapistsinou, MD , Core co-director moderated the webinar.
Watch the webinar video recording here.
Evan and his lab are working to collaborate with scientists of different disciplines on nano-therapeutics. Request a consultation to learn more about how you can use nanocarriers in your research.
Two-time Pilot and Feasibility awardee, Jennie J Lin, MD, MTR recently received the American Society of Nephrology (ASN) 2021 Carl W. Gottschalk Research Scholar Grant. The awarded project titled, Endoplasmic Reticulum Stress and Macrophage Function in APOL1 Nephropathy, studies how genetic variants modulate macrophage function at the intersection of kidney and cardiovascular disease.
Learn more about Dr. Lin and her projects here:
NUGoKidney is excited to welcome its third cohort of scholars into the SciHigh Summer Program. In this summer’s program, 13 students from local Chicago high schools will work with mentors from Northwestern and Loyola on kidney research while gaining exposure to topics and experts in other fields such as pediatrics, genetics, nanoscience, data science, and artificial intelligence. Along with building their fluency in scientific processes, students will participate in a series of professional skills development workshops on project management, time management, networking, and interviewing.
Read about our welcome event and program plan here.
- Northwestern Health Equity Week brings session focused on Kidney Health Equity moderated by NUGoKidney Director06.18.2021
NUGoKidney Director, Susan Quaggin, MD partnered with Feinberg Minority Faculty Association with support from NUCATS to moderate a discussion around racial inequity in kidney care and transplant. During the Kidney Health Equity session, speaker Dinee Simpson, MD addressed the racial biases that impact chances of receiving a kidney transplant. While guest speaker, attending nephrologist and Assistant Professor of Medicine at the University of Pennsylvania, Nwamaka Eneanya, MD, MPH, discussed the inaccuracies in estimated glomerular filtration rate (eGFR), a measurement of kidney function. Ray Bignall, MD, FAAP, FASN, director of Kidney Health Advocacy and Community Engagement at Nationwide Children’s Hospital, rounded out the discussion with an inspiring talk on advocacy in medicine and nephrology, inviting participants to find what helps our “purpose meet [our] passion.”
Watch the recorded session on Kidney Health Equity here (available until August 25, 2021, NetID credentials required).
Find recordings for all Healthy Equity sessions here.
Read the full recap of Health Equity Week here.
NUGoKidney and partners, Melvin Thompson, executive director at The Endeleo Institute and Dinee Simpson, MD, founder of Northwestern Medicine African American Transplant Access Program (AATAP) were one of 21 recipients of Northwestern University's Racial Equity & Community Partnership Grants. The awarded proposal aims to help advance racial equity and address kidney health disparities in communities. Specifically, minimizing the barrier between African Americans and organ transplants by creating access to healthy foods.
NUGoKidney initially partnered with The Endeleo Institute and Dinee Simpson, MD in 2019, thanks to the seeds grant from the Center for Community Health (CCH) Alliance for Research in Chicago Communities (ARCC).
Read more about the funded proposal and other awardees here.
Pinelopi Kapitsinou, MD, co-director of NUGoKidney's Therapeutic Design & Development Core (Core B), and Dan Batlle, MD, NUGoKidney Core B user, recently received NUCATS COVID-19 Collaborative Innovation Awards, which funds new interdisciplinary research and collaboration. Pinelopi Kapitsinou, MD combines expertise in acute kidney injury epidemiology with systems biology knowledge while Dan Batlle, MD pursues the identification of a plasma factor that inhibits binding of SARS-CoV-2 to its host receptor, Angiotensin Converting Enzyme 2 (ACE2).
Read more about NUCATS COVID-19 Collaborative Innovation Award here.
Northwestern’s George M. O’Brien Kidney Research Core Center (NU GoKidney) is joining with other O’Brien Kidney Centers for the National O’Brien Centers Kidney Seminars (NOCKS).
On Friday, March 12th from 11am - 12pm join us for our co-hosted NOCKS featuring Evan Scott, PhD who will discuss his ongoing work of developing rationally designed nanomaterials for controlled targeted therapeutic delivery and potential applications to kidney therapeutics.
NUGoKidney’s SciHigh Program recently joined forces with local non-profit – Color of MedicineTM – to put on a virtual science lab for elementary school students. The first virtual lab kicked off on February 19, 2021 with 3rd grade students from Park Manor Elementary School.
After learning about their mutually shared missions of promoting inclusion of students from underrepresented backgrounds in STEM and medicine, Color of MedicineTM and SciHigh decided to collaborate to bring the magic of science to students through virtual science labs.
Last year on World Kidney Day, we reached nearly 350,000 people with our #sockittokidneydisease campaign, and we're doing it again this year to amplify the World Kidney Day 2021 message on symptom management and patient empowerment so patients with kidney disease can live well and fully participate in every-day life.
Ready your socks and learn how you can sock it to kidney disease.
NUGoKidney's Director - Susan Quaggin, MD, - to lead the American Society of Nephrology in 2021.
During her term as president, the society will focus specifically on eliminating kidney health disparities that will include launching new programs such as the loan mitigation program for trainees underrepresented in medicine, ensuring implementation and access to life- and kidney-saving new therapies such as SGLT2 inhibitors, and harnessing all the transformative advances in the specialty to redefine kidney medicine.
Read the full story here.
Co-director of NUGoKidney's Therapeutic Design & Development Core - Pinelopi Kapitsinou, MD - talks about her work examining the molecular mechanisms by which hypoxic signaling modulates responses to acute kidney injury and how findings in the lab translate to novel diagnostic and therapeutic approaches.
Tamara Isakova, MD, MMSc, director of NUGoKidney's Clinical & Translational Core and the Margaret Gray Morton Professor of Medicine, has been named co-director of the Northwestern University Clinical and Translational Sciences (NUCATS) Institute’s KL2 Program, which supports early-career faculty at Northwestern.
Read more about Isakova's vision for the program here.
On November 19, 2020, we lost a treasure of a human being, H. William Schnaper, MD. An exemplary scientist, Bill contributed greatly to the understanding of childhood glomerulonephritis, as well as factors that contribute to renal fibrosis. But Bill’s love for science and medicine didn’t stop at the lab or the clinic. Unceasingly giving and committed, Bill shared his enthusiasm for science and dedication to mentorship in programs he developed for high school and medical students. As director for NUGoKidney’s Enrichment Program, Bill led the creation of the SciHigh Program, which aims to spark students’ curiosity and develop their confidence and skills to achieve success in science and medicine. Personally and professionally, Bill touched the lives of many with his brilliant scientific mind, generous spirit, and compassion for patients - someone so special can never be forgotten.Read Northwestern’s tribute to Bill here.
While we'll miss seeing our kidney colleagues and community in-person this year, we're excited to connect with you virtually in this year of reimagination!
We have over 50 presentations, sessions, and posters showcasing research from NUGoKidney and Northwestern researchers.
Experts from our Therapeutic Design and Development Core were joined by infectious disease and organ transplant expert, Michael Ison, MD, MS and nephrologist and kidney researcher, Anand Srivastava, MD, MPH to discuss about the impact of COVID-19 on the kidneys; recent research efforts; and therapeutic development opportunities.
Gal Finer, MD, PhD, Assistant Professor of Pediatrics in the Division of Kidney Diseases at Lurie Children’s recently received a 5-year K08 award from the National Institute of Diabetes, Digestive, and Kidney Diseases (NIDDK) to study the molecular mechanisms underlying congenital anomalies of the kidney and urinary tract, or CAKUT – a common birth defect and the leading cause of chronic kidney disease in children.
We are happy to announce the grants awarded from our recent call for proposals for our FY2021 NUGoKidney Pilot & Feasibility (P&F) Program.
- Webinar Recording Now Available: ACE2 Before and After COVID-19: Basic Concepts with Daniel Batlle, MD07.01.2020What is the link between COVID19 and ACE2? Get the answer in this recording from our June 18, 2020 webinar with Daniel Batlle, MD where he discusses ACE2, the renin angiotensin system, and COVID-19.
Click here to view a recording of the webinar.
2018 NUGoKidney Pilot & Feasibility Grant Awardee - Paul DeCaen, PhD - publishes study uncovering the molecular mechanisms behind the development of autosomal dominant polycystic kidney disease (ADPKD), a common genetic disorder characterized by the growth of numerous cysts in the kidneys.
Read more about the study in FSM News here.
Read the publication in Proceedings of the National Academy of Sciences here.
NUGoKidney Pilot & Feasibility awardee, Anand Srivastava, MD, MPH, recently received a five-year K23 award from the National Institute of Diabetes, Digestive, and Kidney Diseases (NIDDK). The study aims to examine whether information about kidney blood flow obtained from contrast enhanced ultrasound (CEUS) will help identify patients with chronic kidney disease (CKD) who are at high risk of experiencing progressive loss of kidney function.
On April 29, 2020, NUGoKidney presented the webinar - CRRT for AKI during the COVID-19 Pandemic - with special guest, Ashita Tolwani, MD from the University of Alabama at Birmingham (UAB).
Dr. Tolwani explained how CRRT prescription might need to be adjusted in regards to modality, dose, and anticoagulation for AKI patients with COVID-19.
Click here to view a recording of the webinar.
Studied by Jing Jin, MD, PhD and his team as a therapy for acute kidney injury (AKI) and hypertension, ACE2-fc, was recently included in an article by Robert Kruse, MD, PhD in F100 Research as a potential therapy for COVID-19.
Dr. Jin talks with NM Better Edge podcast about how the ACE2-fc therapy could potentially be used to guard against and treat COVID-19 and highlights the important role of cross collaboration in facilitating discovery. Listen now here.
Over 70 high school juniors from Holy Trinity High School participated in the SciHigh workshop - Data IRL: Thinking Big & Improving Health - focused on real-world uses of data and computing in medicine and health research.