- Provide solutions to enhance small molecule treatment outcomes while reducing undesirable, off-target side effects.
- Enable kidney investigators to apply nanotechnology to address a range of research questions
- Develop SOPs and QA/QC control.
Biomedical Resource Core Services
Guidance in Molecular and Cell Target SelectionOur Core co-directors will assist in identifying specific molecular targets for precise drug and payload delivery in the kidney.
Nanoparticle Carrier Selection Assistance:Co-directors will aid in choosing suitable nanocarriers that align with molecular targets for specific kidney sub-regions.
Synthesis and Attachment of Targeting Moieties
After selecting ligands and appropriate nanocarriers, the Core will oversee the synthesis of targeting moieties, leveraging the capabilities of the Peptide Synthesis Core for varied-scale production.
Gene Therapy and Drug Loading into Nanocarriers
The Core will facilitate the incorporation of therapeutic payloads into nanoparticles, utilizing various strategies based on the cargo and application.