BRC – Biomedical Resource Core
BRC Mission
Advance kidney research through innovative nanotechnology
The Biomedical Resource Core (BRC) provides investigators with access to robust, established, and ready-to-use nanotechnology services designed to address the complexity of kidney tissues and cellular diversity. By integrating advances in the physical sciences with kidney research, the BRC enables innovative approaches to studying disease mechanisms, developing targeted therapies, and advancing disease monitoring. Our services include Mouse Models for kidney biology and disease research, Nanotechnology Solutions to address diverse research questions, and Short RNA Delivery using nanocarriers to target the kidney.
BRC Services
Explore our service categories below to learn how the Biomedical Resource Core can support your research. To request a service, click the Request button below to access the OKRA Resource Consultation Form. Select NU-USC as the resource center, then in the “In a few short sentences, please tell us your project needs or list the resource(s) you intend to request from the selected center(s)” field, enter the service you are requesting and any additional information that may help us prepare for your consultation.
Mouse Lines
We provide established genetically engineered mouse lines for studying kidney development, renal disease, vascular biology, and related signaling pathways.Guidance in Molecular and Cell Target Selection
We will assist in identifying specific molecular targets for precise drug and payload delivery in the kidney.Nanoparticle Carrier Selection Assistance
We will aid in choosing suitable nanocarriers that align with molecular targets for specific kidney sub-regions.Synthesis and Attachment of Targeting Moieties
After selecting ligands and appropriate nanocarriers, we will oversee the synthesis and coupling of targeting moieties to nanocarriers.Gene Therapy and Drug Loading into Nanocarriers
We will facilitate the incorporation of therapeutic payloads into nanoparticles, utilizing various strategies based on the cargo and application.
Evaluating Targeting Fidelity
We will provide expertise in assessing the targeting accuracy of nanotherapeutics both in lab settings and live subjects.Short RNA Delivery Solutions
We will provide specialized services for the development and optimization of short RNA delivery methods, with a focus on targeted delivery to kidney cells using peptide ligands
Our BRC Team
BRC Director
Eunji Chung, PhD
Associate Professor of Biomedical Engineering
University of Southern California
BRC Navigator
Yunxi Chen, PhD
Postdoctoral Researcher
University of Southern California