BRC – Biomedical Resource Core
Get StartedBRC Mission
Advance kidney research through innovative nanotechnology
The Biomedical Resource Core (BRC) provides investigators with access to robust, established, and ready-to-use nanotechnology services designed to address the complexity of kidney tissues and cellular diversity. By integrating advances in the physical sciences with kidney research, the BRC enables innovative approaches for studying disease mechanisms, developing targeted therapies, and advancing disease monitoring.
BRC Services
Guidance in Molecular and Cell Target Selection
We will assist in identifying specific molecular targets for precise drug and payload delivery in the kidney.Nanoparticle Carrier Selection Assistance:
We will aid in choosing suitable nanocarriers that align with molecular targets for specific kidney sub-regions.Synthesis and Attachment of Targeting Moieties
After selecting ligands and appropriate nanocarriers, the Core will oversee the synthesis of targeting moieties, leveraging the capabilities of the Peptide Synthesis Core for varied-scale production.
Gene Therapy and Drug Loading into Nanocarriers
We will facilitate the incorporation of therapeutic payloads into nanoparticles, utilizing various strategies based on the cargo and application.
Evaluating Targeting Fidelity In Vitro
We will provide expertise in assessing the targeting accuracy of nanotherapeutics both in lab settings and live subjects.Short RNA Delivery Solutions
Our team specializes in developing and optimizing short RNA delivery methods, specifically targeting kidney cells using peptide ligands.Our BRC Team
BRC Director
Eunji Chung, PhD
Associate Professor of Biomedical Engineering
University of Southern California
BRC Navigator
Yunxi Chen, PhD
Postdoctoral Researcher
University of Southern California